Tin lượng bệnh nhân đái tháo đường bị Nocs

Tin lượng bệnh nhân đái tháo đường bị Nocs

Nhóm thuốc incretin (bao gồm đồng vận của GLP-1 và ức chế DPP-4) có tác dụng cải thiện kết quả nhồi máu cơ tim ST không chênh lên (non-ST-elevation myocardial infarction (NSTEMI)) ở bệnh nhân đái tháo đường typ 2 (ĐTĐ) và xơ vữa động mạch không tắc nghẽn (non-obstructive coronary artery stenosis (NOCS)) theo như một nghiên cứu được đăng trên tạp chí online Diabetes, Obesity and Metabolism ngày 26/9/2017.

TIN LƯỢNG BỆNH NHÂN ĐÁI THÁO ĐƯỜNG BỊ NOCS - NSTEMI ĐƯỢC CẢI THIỆN KHI SỬ DỤNG NHÓM THUỐC INCRETIN

Nhóm thuốc incretin (bao gồm đồng vận của GLP-1 và ức chế DPP-4) có tác dụng cải thiện kết quả nhồi máu cơ tim ST không chênh lên (non-ST-elevation myocardial infarction (NSTEMI)) ở bệnh nhân đái tháo đường typ 2 (ĐTĐ) và xơ vữa động mạch không tắc nghẽn (non-obstructive coronary artery stenosis (NOCS)) theo như một nghiên cứu được đăng trên tạp chí online Diabetes, Obesity and Metabolism ngày 26/9/2017.

Tiến sỹ Raffaele Marfella từ Trường Đại học degli Studi della Campania, Ý và cộng sự đã so sánh tin lượng của những bệnh nhân bị NOCS (hẹp 20-49%), NSTEMI kèm theo bị ĐTĐ và bệnh nhân không bị ĐTĐ trong vòng 12 tháng. Họ cũng so sánh tin lượng của những bệnh nhân trước đó đã điều trị với nhóm thuốc incretin (6 tháng) và những bệnh nhân chưa bao giờ điều trị bằng incretin.

Các nhà nghiên cứu đã nhận thấy rằng tử vong do mọi nguyên  nhân, tử vong do tim mạch, tái bị hội chứng mạch vàng cấp và suy tim ở bệnh nhân ĐTĐ cao hơn bệnh nhân không bị ĐTĐ. Trong số những bệnh nhân ĐTĐ, những người hiện đang sử dụng incretin có tỷ lệ tử vong do mọi nguyên nhân, do bệnh lý tim mạch và tái bị hội chứng mạch vành cấp thấp hơn có ý nghĩa so với những bệnh nhân không sử dụng incretin trong suốt 12 tháng.

“Ở bệnh nhân ĐTĐ typ 2 bị NOCS-NSTEMI, chúng tôi quan sát thấy tỷ lệ tử vong một năm và những kết cục bất lợi về tim mạch cao hơn khi so sánh với những bệnh nhân bị NOCS-NSTEMI không kèm ĐTĐ. Đối với những bệnh nhân ĐTĐ chưa bao giờ sử dụng incretin có tin lượng xấu hơn khi so sánh với những bệnh nhân hiện đang sử dụng incretin”, các tác giả kết luận.

                                   FRIDAY, Oct. 27, 2017 (HealthDay News), Physician’s Briefing

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